CHRM1 Goat Polyclonal Antibody

CAT#: TA302450

Goat Polyclonal Antibody against Cholinergic receptor / CHRM1



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CNY 5,371.00


货期*
4周

规格
    • 100 ug

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经常一起买 (2)
Transient overexpression lysate of cholinergic receptor, muscarinic 1 (CHRM1)
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:16,000. WB: 1-3µg/ml.
Reactivity Human, Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence C-DKRRWRKIPKRPGSVH, from the C Terminus of the protein sequence according to NP_000729.2.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 55048 Da
Gene Name cholinergic receptor muscarinic 1
Background The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq]
Synonyms HM1; M1; M1R
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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