EHD2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, PEP-ELISA, WB
Recommend Dilution	ELISA: 1:32,000. WB: 0.003-0.01µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence CRLVPPSKRRHKGSA, from the C Terminus of the protein sequence according to NP_055416.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	64790 Da
Gene Name	EH domain containing 2
Database Link	NP_055416 Entrez Gene 259300 MouseEntrez Gene 361512 RatEntrez Gene 484417 DogEntrez Gene 30846 Human UniProt ID Q9NZN4
Background	This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. COMPLETENESS: complete on the 3' end.
Synonyms	PAST2
Reference Data
Protein Pathways	Endocytosis

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