PARK7 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, PEP-ELISA, WB
Recommend Dilution	WB: 0.05-0.1 µg/ml.
Reactivity	Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-AAQVKAPLVLKD, from the C Terminus of the protein sequence according to NP_009193.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19.7 kDa
Gene Name	Parkinsonism associated deglycase
Database Link	NP_009193 Entrez Gene 57320 MouseEntrez Gene 117287 RatEntrez Gene 11315 Human UniProt ID Q99497
Background	The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]
Synonyms	DJ-1; DJ1; HEL-S-67p
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Parkinson's disease

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