MDA5 (IFIH1) Goat Polyclonal Antibody
CAT#: TA302870
Goat Polyclonal Antibody against IFIH1 (MDA5)
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CNY 5,371.00
CNY 4,840.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 9,998.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | ELISA: 1:32,000. WB: 10µg/ml. |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence SNGYSTDENFRYL-C, from the N Terminus of the protein sequence according to NP_071451.2. |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | interferon induced with helicase C domain 1 |
Database Link | |
Background | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. [provided by RefSeq] |
Synonyms | AGS7; Hlcd; IDDM19; MDA-5; MDA5; RLR-2 |
Reference Data | |
Protein Pathways | RIG-I-like receptor signaling pathway |
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