ARH (LDLRAP1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:16,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence DALKSAGRALIRS-C, from the N Terminus of the protein sequence according to NP_056442.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	low density lipoprotein receptor adaptor protein 1
Database Link	NP_056442 Entrez Gene 100017 MouseEntrez Gene 500564 RatEntrez Gene 612219 DogEntrez Gene 26119 Human UniProt ID Q5SW96
Background	The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq]
Synonyms	ARH; ARH1; ARH2; FHCB1; FHCB2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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