Col7a1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:32,000. WB: 0.1-1.5µg/ml.
Reactivity	Rat, Human, Mouse, Dog, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-TVQYSDDPRTEF, from the internal region of the protein sequence according to NP_000085.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	collagen, type VII, alpha 1
Database Link	NP_001100328 Entrez Gene 1294 HumanEntrez Gene 12836 MouseEntrez Gene 403467 DogEntrez Gene 301012 Rat
Background	This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq]
Synonyms	EBD1; EBDCT; EBR1
Reference Data

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