FBXL3 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:32,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence KRGGRDSDRNSSEE-C, from the N Terminus of the protein sequence according to NP_036290.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	F-box and leucine-rich repeat protein 3
Database Link	NP_036290 Entrez Gene 50789 MouseEntrez Gene 306129 RatEntrez Gene 485499 DogEntrez Gene 26224 Human UniProt ID Q9UKT7
Background	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	FBL3; FBL3A; FBXL3A
Reference Data
Protein Families	Druggable Genome

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