GCKR Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 0.1-0.3ug/ml.
Reactivity	Mouse, Rat, Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence KRFQHVIETPEPGK-C, from the N-Terminus of the protein sequence according to NP_001477.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	glucokinase (hexokinase 4) regulator
Database Link	NP_001477 Entrez Gene 25658 RatEntrez Gene 231103 MouseEntrez Gene 2646 Human UniProt ID Q14397
Background	This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq]
Synonyms	FGQTL5; GKRP
Reference Data

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