SFRP4 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1-3 µg/ml. IHC: 2-4 µg/ml.
Reactivity	Human, Mouse, Rat, Cow, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence TNSSCQCPHILPHQD, from the internal region of the protein sequence according to NP_003005.2.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	secreted frizzled related protein 4
Database Link	NP_003005 Entrez Gene 20379 MouseEntrez Gene 89803 RatEntrez Gene 6424 Human UniProt ID Q6FHJ7
Background	Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq]
Synonyms	FRP-4; FRPHE; sFRP-4
Note	IHC: In paraffin embedded Human Uterus shows granular staining in the apical cytoplasm of the endometrial gland.
Reference Data
Protein Families	Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways	Wnt signaling pathway

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