Dispatched (DISP1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	IF: 2.5ug/ml.
Reactivity	Human, Mouse, Rat, Pig
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-SELSGESLLIKTL, from the C Terminus of the protein sequence according to NP_116279.2.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dispatched RND transporter family member 1
Database Link	NP_116279 Entrez Gene 68897 MouseEntrez Gene 289338 RatEntrez Gene 84976 Human UniProt ID Q96F81
Background	The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	DISPA
Reference Data
Protein Families	Transmembrane

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