Calnexin (CANX) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, PEP-ELISA, WB
Recommend Dilution	WB: 0.3-1ug/ml. IHC: 3-6ug/ml.
Reactivity	Human, Mouse, Rat, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-SKTPELNLDQFHDKT, from the internal region (near N-Terminus) of the protein sequence according to NP_001737.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calnexin
Database Link	NP_001019820 Entrez Gene 12330 MouseEntrez Gene 29144 RatEntrez Gene 403908 DogEntrez Gene 821 Human UniProt ID P27824
Background	This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
Synonyms	CNX; IP90; P90
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Antigen processing and presentation

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