TLR1 Rabbit Polyclonal Antibody
CNY 5,808.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | ELISA, ICC, WB |
Recommend Dilution | TLR1 antibody can be used for detection of TLR1 by Western blot at 1 to 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 10 µg/mL. Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | TLR1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human TLR1. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | TLR1 Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | toll like receptor 1 |
Database Link | |
Background | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7). |
Synonyms | CD281; rsc786; TIL; TIL. LPRS5 |
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