IL27 Rabbit Polyclonal Antibody

CAT#: TA306317

Rabbit Polyclonal IL-27 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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经常一起买 (2)
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 2 - 4 ug/mL
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen IL-27 antibody was raised against a 14 amino acid peptide from near the center of human IL-27.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name interleukin 27
Background Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
Synonyms IL-27; IL-27A; IL27A; IL27p28; IL30; p28
Reference Data
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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