MD1 (LY86) Rabbit Polyclonal Antibody

CAT#: TA306330

Rabbit Polyclonal MD-1 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen MD-1 antibody was raised against a 15 amino acid peptide from near the center of human MD-1.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name lymphocyte antigen 86
Background Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Synonyms dJ80N2.1; MD-1; MD1; MMD-1
Reference Data
Protein Families Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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