Apolipoprotein A I (APOA1) Chicken Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Chicken
Clonality	Polyclonal
Immunogen	ApoA1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ApoA1. The immunogen is located within the first 50 amino acids of ApoA1.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Affinity chromatography purified via peptide column
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	apolipoprotein A1
Database Link	NP_000030 Entrez Gene 11806 MouseEntrez Gene 25081 RatEntrez Gene 335 Human UniProt ID P02647
Background	Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.
Synonyms	apo(a)
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	PPAR signaling pathway

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