Tnfaip3 Rabbit Polyclonal Antibody

CAT#: TA306770

Rabbit Polyclonal TNFAIP3 Antibody



Need it in bulk or conjugated?
Get a free quote

CNY 5,808.00


货期*
5周

规格
    • 100 ug

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human tumor necrosis factor, alpha-induced protein 3 (TNFAIP3), 100 µg
    • 100 ug

CNY 9,998.00


Transient overexpression lysate of tumor necrosis factor, alpha-induced protein 3 (TNFAIP3)
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen TNFAIP3 antibody was raised against a 17 amino acid peptide near the center of human TNFAIP3.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name tumor necrosis factor, alpha-induced protein 3
Background TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kB-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.
Synonyms A20; OTUD7C; TNFA1P2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...