TMEM184A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	TMEM184A antibody can be used for detection of TMEM184A by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TMEM184A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TMEM184A.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TMEM184A Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Gene Name	transmembrane protein 184A
Database Link	NP_001091089 Entrez Gene 231832 MouseEntrez Gene 304325 RatEntrez Gene 202915 Human UniProt ID Q6ZMB5
Background	TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.
Synonyms	SDMG1
Reference Data
Protein Families	Transmembrane

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