Desmocollin 2 (DSC2) Rabbit Polyclonal Antibody

CAT#: TA307897

Rabbit polyclonal antibody to Desmocollin 2 (desmocollin 2)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

Product images

经常一起买 (4)
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Purified recombinant protein of Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2b, 20 µg
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Purified recombinant protein of Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2b, 100 µg
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 480 and 706 of Desmocollin 2 (Uniprot ID#Q02487)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 94 kDa
Gene Name desmocollin 2
Background The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq]
Synonyms ARVD11; CDHF2; DG2; DGII; DSC3; III
Note Seq homology of immunogen across species: Mouse (80%)
Reference Data
Protein Families Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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