coproporphyrinogen oxidase (CPOX) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 139 and 423 of CPOX (Uniprot ID#P36551)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50 kDa
Gene Name	coproporphyrinogen oxidase
Database Link	NP_000088 Entrez Gene 12892 MouseEntrez Gene 304024 RatEntrez Gene 1371 Human UniProt ID P36551
Background	Coproporphyrinogen oxidase (EC 1.3.3.3) is the sixth enzyme of the heme biosynthetic pathway. This soluble protein is localized in the intermembrane space of mitochondria and catalyzes the conversion of 2 propionate groups at positions 2 and 4 of coproporphyrinogen III to 2 vinyl groups of protoporphyrinogen IX. [supplied by OMIM]
Synonyms	CPO; CPX; HCP
Note	Seq homology of immunogen across species: Mouse (89%), Rat (88%), Bovine (94%)
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Porphyrin and chlorophyll metabolism

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