TPP1 Rabbit Polyclonal Antibody

CAT#: TA308202

Rabbit polyclonal antibody to CLN2 (tripeptidyl peptidase I)



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CNY 6,281.00


货期*
4周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human, Chimpanzee
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 224 and 563 of CLN2 (Uniprot ID#O14773)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 61 kDa
Gene Name tripeptidyl peptidase 1
Background This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq]
Synonyms CLN2; GIG1; LPIC; SCAR7; TPP-1
Note Seq homology of immunogen across species: Chimpanzee (100%)
Reference Data
Protein Families Protease
Protein Pathways Lysosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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