Importin 7 (IPO7) Rabbit Polyclonal Antibody

CAT#: TA308330

Rabbit Polyclonal antibody to Importin 7 (importin 7)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Applications IF, IHC, WB
Recommend Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human, Mouse, Rat, Zebrafish, Xenopus, Bovine, X. tropicalis
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region within amino acids 976 and 1038 of Importin 7 (Uniprot ID#O95373)
Formulation 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 120 kDa
Gene Name importin 7
Background The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq]
Synonyms Imp7; RANBP7
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (85%), Xenopus Tropicalis (92%), Bovine (100%)
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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