OSBPL2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Xenopus, Chicken, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 418 and 480 of OSBPL2 (Uniprot ID#Q9H1P3)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54 kDa
Gene Name	oxysterol binding protein like 2
Database Link	NP_055650 Entrez Gene 228983 MouseEntrez Gene 296461 RatEntrez Gene 9885 Human UniProt ID Q9H1P3
Background	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq]
Synonyms	DFNA67; DNFA67; ORP-2; ORP2
Note	Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (85%), Xenopus Tropicalis (85%), Chicken (92%)
Reference Data

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