Meckelin (TMEM67) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 231 and 510 of meckelin isoform 1 (Uniprot ID#Q5HYA8)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	112 kDa
Gene Name	transmembrane protein 67
Database Link	NP_001135773 Entrez Gene 313067 RatEntrez Gene 329795 MouseEntrez Gene 91147 Human UniProt ID Q5HYA8
Background	The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6). [provided by RefSeq]
Synonyms	JBTS6; MECKELIN; MKS3; NPHP11; TNEM67
Note	Seq homology of immunogen across species: Mouse (82%), Rat (81%), Bovine (88%)
Reference Data
Protein Families	Transmembrane

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