CD41 (ITGA2B) Rabbit Polyclonal Antibody
CAT#: TA308579
Rabbit polyclonal antibody to CD41/Integrin alpha 2b (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41))
Need it in bulk or conjugated?
Get a free quote
CNY 6,281.00
Cited in 2 publications. |
CNY 4,840.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivity | Human, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 210 and 532 of Integrin alpha 2b (Uniprot ID#P08514) |
Formulation | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 113 kDa |
Gene Name | integrin subunit alpha 2b |
Database Link | |
Background | ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq] |
Synonyms | BDPLT2; BDPLT16; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93 |
Note | Seq homology of immunogen across species: Dog (88%), Bovine (86%) |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
αvβ3 integrin expression increases elasticity in human melanoma cells
,Lacaria, L;Lange, JR;Goldmann, WH;Rico, F;Alonso, JL;,
Biochem. Biophys. Res. Commun.
,PubMed ID 32164941
[ITGA2B]
|
Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit(Wv) Mutations
,Yurino, A;Takenaka, K;Yamauchi, T;Nunomura, T;Uehara, Y;Jinnouchi, F;Miyawaki, K;Kikushige, Y;Kato, K;Miyamoto, T;Iwasaki, H;Kunisaki, Y;Akashi, K;,
Stem Cell Reports
,PubMed ID 27499200
[ITGA2B]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |