IDI1 Rabbit Polyclonal Antibody
CAT#: TA308665
Rabbit polyclonal antibody to IDI1 (isopentenyl-diphosphate delta isomerase 1)
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CNY 6,281.00
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | IHC:1:100-1:1000; WB:1:500-1:3000 |
Reactivity | Human, Mouse, Rat, Xenopus, Zebrafish, Bovine, X. tropicalis |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant fragment corresponding to a region within amino acids 1 and 173 of IDI1 (Uniprot ID#Q13907) |
Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 32 kDa |
Gene Name | isopentenyl-diphosphate delta isomerase 1 |
Database Link | |
Background | IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq] |
Synonyms | IPP1; IPPI1 |
Note | Seq homology of immunogen across species: Mouse (87%), Rat (85%), Xenopus laevis (80%), Zebrafish (81%), Bovine (89%), Xenopus tropicalis (81%) |
Reference Data | |
Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
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