Factor IX (F9) Rabbit Polyclonal Antibody

CAT#: TA308875

Rabbit polyclonal antibody to Factor IX (coagulation factor IX)



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CNY 6,281.00


货期*
5周

规格
    • 100 ul

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经常一起买 (2)
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Specifications

Product Data
Applications IHC, WB
Recommend Dilution IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human, Mouse, Dog, Monkey, Pig, Rabbit, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 217 and 453 of Factor IX (Uniprot ID#P00740)
Formulation 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 52 kDa
Gene Name coagulation factor IX
Background This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq]
Synonyms FIX; HEMB; P19; PTC; THPH8
Note Seq homology of immunogen across species: Mouse (80%), Dog (87%), Monkey (96%), Pig (87%), Rabbit (82%), Rat (82%), Bovine (82%)
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Complement and coagulation cascades
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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