Phospholipase c eta 1 (PLCH1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 548 and 871 of PLCH1 (Uniprot ID#Q4KWH8)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	185 kDa
Gene Name	phospholipase C eta 1
Database Link	NP_001124433 Entrez Gene 269437 MouseEntrez Gene 310463 RatEntrez Gene 23007 Human UniProt ID Q4KWH8
Background	PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]). [supplied by OMIM]
Synonyms	PLCL3
Note	Seq homology of immunogen across species: Mouse (99%), Rat (98%)
Reference Data
Protein Families	Druggable Genome

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