Haptoglobin (HP) Goat Polyclonal Antibody

CAT#: TA309543

Goat Polyclonal Antibody against HP alpha chain



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CNY 5,371.00


货期*
5周

规格
    • 100 ug

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经常一起买 (4)
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Recombinant protein of human haptoglobin (HP), transcript variant 1, 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution WB: 0.01-0.03ug/ml
Reactivity Human
Host Goat
Clonality Polyclonal
Immunogen Peptide with sequence QCKNYYKLRTEGD, from the internal region of the protein sequence according to NP_005134.1; NP_001119574.1.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name haptoglobin
Background This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms BP; HP2ALPHA2; HPA1S
Reference Data
Protein Families Druggable Genome, Protease, Secreted Protein, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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