BCAR1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:500~3000, IHC: 1:50~1:100, ELISA: 1:5000
Reactivity	Human: Tyr410, Mouse: Tyr414, Rat: Tyr508
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human p130 Cas around the phosphorylation site of tyrosine 410 (G-V-YP-A-V).
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	BCAR1, Cas family scaffolding protein
Database Link	NP_055382 Entrez Gene 12927 MouseEntrez Gene 25414 RatEntrez Gene 9564 Human UniProt ID P56945
Synonyms	CAS; CAS1; CASS1; CRKAS; P130Cas
Note	p130 Cas (Phospho-Tyr410) antibody detects endogenous levels of p130 Cas only when phosphorylated at tyrosine 410.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton

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