NEI3 (NEIL3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~1:3000 ELISA: 1:40000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized peptide derived from internal of human NEIL3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	nei like DNA glycosylase 3
Database Link	NP_060718 Entrez Gene 234258 MouseEntrez Gene 55247 Human UniProt ID Q8TAT5
Background	NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]). [supplied by OMIM, Mar 2008]
Synonyms	FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
Note	NEIL3 antibody detects endogenous levels of total NEIL3 protein.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Base excision repair

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.