PLAUR Rabbit Polyclonal Antibody
CNY 4,477.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 0.5-1 ug/ml |
Reactivity | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide surrounding amino acid 51 of rat uPAR |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in 1X phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal. |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | plasminogen activator, urokinase receptor |
Database Link | |
Background | uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis. |
Synonyms | CD87; U-PAR; UPAR; URKR |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Complement and coagulation cascades |
Documents
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