LIM Kinase 1 (LIMK1) Rabbit Polyclonal Antibody
CAT#: TA319157
Rabbit polyclonal LIM Kinase antibody
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CNY 8,025.00
货期*
5周
规格
经常一起买 (3)
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1:8,000 - 1:36,000, WB: 1:500 - 1:2,000, IF: User Optimized |
Reactivity | Human, Chimpanzee, Orang-Utan |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 630-647 of human LIM kinase protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | LIM domain kinase 1 |
Database Link | |
Synonyms | LIMK; LIMK-1 |
Note | LIM Kinase is also known as LIM-domain containing protein kinase, LIMK-1 and LIMK. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
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