IL10 Rabbit Polyclonal Antibody

CAT#: TA319291

Rabbit polyclonal anti-IL-10 antibody



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CNY 20,681.00


货期*
5周

规格
    • 1 ml

Product images

经常一起买 (4)
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Purified recombinant protein of Homo sapiens interleukin 10 (IL10), 20 µg
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Purified recombinant protein of Homo sapiens interleukin 10 (IL10), 100 µg
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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:20,000 - 1:100,000, WB: 1:2,000 - 1:10,000, IHC: 1:1,000 - 1:5,000
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen The whole rabbit serum was prepared by repeated immunizations with human IL-10.
Formulation None
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name interleukin 10
Synonyms CSIF; GVHDS; IL-10; IL10A; TGIF
Note Anti IL-10 Antibody recognizes IL-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), that is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. IL-10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-?B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract and indeed patients with Crohn's disease react favorably towards treatment with bacteria producing recombinant interleukin 10, showing the importance of interleukin 10 for counteracting excessive immunity in the human body. Anti-IL-10 cytokine antibody is ideal for investigators involved Immunology and Signal Transduction research.
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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