Apc10 (ANAPC10) Rabbit Polyclonal Antibody

CAT#: TA319413

Rabbit polyclonal anti-APC10 antibody



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CNY 8,025.00


货期*
5周

规格
    • 100 ug

Cited in 1 publication.

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:15,000 - 1:80,000, WB: 1:500 - 1:1,500, IHC: 1:250 - 1:1,000, IP: 1:100
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name anaphase promoting complex subunit 10
Synonyms APC10; DOC1
Note APC (Anaphase-Promoting Complex or Cyclosome) is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds1/Cut2 and cyclin B. It was found that APC10/Doc1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid-body in telophase and cytokinesis. These results strongly support the notion that human APC10/Doc1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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