Il1b Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:10,000-1:50,000, WB: 1:1,000-1:5,000, IHC: 1:500-1:2,500
Reactivity	Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody was prepared by repeated immunizations with recombinant mouse IL-1β produced in E.coli. The MW of recombinant mouse IL-1β was 17 kDa.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Conjugation	Peroxidase
Storage Condition	Store at -20°C as received.
Gene Name	interleukin 1 beta
Database Link	NP_032387 Entrez Gene 24494 RatEntrez Gene 16176 Mouse UniProt ID P10749
Synonyms	catabolin; IL-1; IL-1B; IL1-BETA; IL1F2; pro-interleukin-1-beta
Note	IL-1 beta (also known as Interleukin-1 beta, IL-1β and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1β is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Reference Data

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