GPR48 (LGR4) Mouse Monoclonal Antibody [Clone ID: 6G8.B3.G5.C3]

Specifications

Product Data
Clone Name	6G8.B3.G5.C3
Applications	IHC
Recommend Dilution	ELISA: 1:20,000 - 1:100,000, WB: 1:500 - 1:3,000, IHC: 5 ug/mL
Reactivity	Human, Chimpanzee, Macaque
Host	Mouse
Clonality	Monoclonal
Immunogen	This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.
Formulation	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	leucine-rich repeat containing G protein-coupled receptor 4
Database Link	NP_060960 Entrez Gene 55366 Human UniProt ID Q9BXB1
Synonyms	BNMD17; GPR48
Note	LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane

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