Nucleobindin 2 (NUCB2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Nucleobindin-2 antibody was raised against a 16 amino acid peptide near the center of human Nucleobindin-2 .
Formulation	Nucleobindin-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Nucleobindin-2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 46 kDa; Observed: 54 kDa
Gene Name	nucleobindin 2
Database Link	NP_005004 Entrez Gene 53322 MouseEntrez Gene 59295 RatEntrez Gene 4925 Human UniProt ID P80303
Background	Nucleobindin-2 Antibody: NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
Synonyms	HEL-S-109; NEFA
Reference Data
Protein Families	Secreted Protein, Transmembrane

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