BCAR3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	BCAR3 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BCAR3.
Formulation	BCAR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	BCAR3 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	91 kDa
Gene Name	breast cancer anti-estrogen resistance 3
Database Link	NP_003558 Entrez Gene 8412 Human UniProt ID O75815
Background	BCAR3 Antibody: Breast cancer anti-estrogen resistance 3 (BCAR3) was identified in the search for genes involved in the development of estrogen resistance. It contains a putative src homology 2 (SH2) domain and is partly homologous to the cell division cycle protein CDC48. BCAR3 is a binding partner with Cas, an adapter molecule that plays a role in cell proliferation, survival, cell adhesion, and mobility. BCAR3 functions synergistically with Cas to enhance Src activation and promote cell migration, and has been suggested to regulate Cas/Src association, Src kinase activity, and breast cancer adhesion signaling.
Synonyms	NSP2; SH2D3B
Reference Data

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