TBC1D4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	ICC: 10 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	TBC1D4 antibody was raised against an 19 amino acid peptide near the carboxy terminus of human TBC1D4 .
Formulation	TBC1D4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	TBC1D4 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 143 kDa; Observed: 140 kDa
Gene Name	TBC1 domain family member 4
Database Link	NP_055647 Entrez Gene 9882 Human UniProt ID O60343
Background	TBC1D4 Antibody: TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes.
Synonyms	AS160; NIDDM5
Reference Data

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