Bim (BCL2L11) Mouse Monoclonal Antibody [Clone ID: 1C2H4]

Specifications

Product Data
Clone Name	1C2H4
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Mouse monoclonal Bim antibody was raised against a recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Formulation	Bim Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	Bim Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	BCL2 like 11
Database Link	NP_619527 Entrez Gene 10018 Human UniProt ID O43521
Background	Bim Monoclonal Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Synonyms	BAM; BIM; BOD
Reference Data

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