ATP11B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	ATP11B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11B.
Formulation	ATP11B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	ATP11B Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ATPase phospholipid transporting 11B (putative)
Database Link	NP_055431 Entrez Gene 76295 MouseEntrez Gene 23200 Human UniProt ID Q9Y2G3
Background	ATP11B Antibody: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Synonyms	ATPIF; ATPIR
Reference Data
Protein Families	Transmembrane

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