Lymphocyte Antigen 6 Complex (LY6K) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	LY6K antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human LY6K.
Formulation	LY6K Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	LY6K Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lymphocyte antigen 6 complex, locus K
Database Link	NP_059997 Entrez Gene 76486 MouseEntrez Gene 100363492 RatEntrez Gene 54742 Human UniProt ID Q17RY6
Background	LY6K Antibody: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer. LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues. LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification. Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.
Synonyms	CT97; HSJ001348; ly-6K; URLC10
Reference Data
Protein Families	Transmembrane

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