KCNK13 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KCNK13 antibody was raised against a 15 amino acid synthetic peptide near the center of human KCNK13.
Formulation	KCNK13 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	KCNK13 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	potassium two pore domain channel subfamily K member 13
Database Link	NP_071337 Entrez Gene 64120 RatEntrez Gene 217826 MouseEntrez Gene 56659 Human UniProt ID Q9HB14
Background	KCNK13 Antibody: The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.
Synonyms	K2p13.1; THIK-1; THIK1
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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