MYCT1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
Formulation	MYCT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	MYCT1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	26 kDa
Gene Name	myc target 1
Database Link	NP_079383 Entrez Gene 68632 MouseEntrez Gene 292264 RatEntrez Gene 80177 Human UniProt ID Q8N699
Background	MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Synonyms	MTLC
Reference Data
Protein Families	Transmembrane

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