KHDC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	KHDC1 antibody was raised against a 15 amino acid peptide near the amino terminus of human KHDC1.
Formulation	KHDC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	KHDC1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 18 kDa; Observed: 26 kDa
Gene Name	KH homology domain containing 1
Database Link	NP_085045 Entrez Gene 689090 RatEntrez Gene 80759 Human UniProt ID Q4VXA5
Background	KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).
Synonyms	bA257K9.4; C6orf147; C6orf148; Em:AC019205.8; NDG1
Reference Data
Protein Families	Transmembrane

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