VARP (ANKRD27) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5 ug/mL
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP.
Formulation	VARP Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	VARP Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ankyrin repeat domain 27
Database Link	NP_115515 Entrez Gene 84079 Human UniProt ID Q96NW4
Background	VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
Synonyms	PP12899; VARP
Reference Data

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