NLRC5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	NOD4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NOD4.
Formulation	NOD4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	NOD4 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	NLR family, CARD domain containing 5
Database Link	NP_115582 Entrez Gene 434341 MouseEntrez Gene 84166 Human UniProt ID Q86WI3
Background	NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
Synonyms	CLR16.1; NOD4; NOD27
Reference Data

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