ZGPAT Chicken Polyclonal Antibody
CNY 5,808.00
货期*
5周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IF, WB |
Recommend Dilution | WB: 1 ug/mL, IF: 20 ug/mL |
Reactivity | Human |
Host | Chicken |
Clonality | Polyclonal |
Immunogen | ZGPAT antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT. |
Formulation | ZGPAT Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | ZGPAT Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | zinc finger CCCH-type and G-patch domain containing |
Database Link | |
Background | ZGPAT Antibody: The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT. |
Synonyms | CCCH-type with G patch domain; GPATC6; GPATCH6; KIAA1847; MGC44880; OTTHUMP00000031593; OTTHUMP00000031594; OTTHUMP00000031596; RP4-583P15.3; ZC3H9; ZC3HDC9; zinc finger |
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