SPINK7 Chicken Polyclonal Antibody

CAT#: TA320055

Chicken Polyclonal ECRG2 Antibody



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CNY 5,808.00


货期*
5周

规格
    • 100 ug

Product images

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 1 ug/mL, ICC: 5 ug/mL
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Immunogen ECRG2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG2.
Formulation ECRG2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification ECRG2 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name serine peptidase inhibitor, Kazal type 7 (putative)
Background ECRG2 Antibody: The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.
Synonyms ECG2; ECRG2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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