GBP5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 .
Formulation	GBP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	GBP5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 64 kDa; Observed: 66 kDa
Gene Name	guanylate binding protein 5
Database Link	NP_443174 Entrez Gene 115362 Human UniProt ID Q96PP8
Background	GBP5 Antibody: The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
Synonyms	GBP-5
Reference Data

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